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Medication Safety in Pregnancy

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Pregnant Mother with Tablet and Water



Antidepressant prescriptions, discontinuation, depression and perinatal outcomes, including breastfeeding: A population cohort analysis. (2019) Jordan S, Davies GI, Thayer DS, Tucker D, Humphreys I. PLOS ONE 14(11): e0225133.  


Selective Serotonin Reuptake Inhibitor (SSRI) Antidepressants in Pregnancy and Congenital Anomalies: Analysis of Linked Databases in Wales, Norway and Funen, Denmark. Sue Jordan, Joan K. Morris, Gareth I. Davies, David Tucker, Daniel S. Thayer, Johannes M. Luteijn, Margery Morgan, Ester Garne, Anne V. Hansen, Kari Klungsøyr, Anders Engeland, Breidge Boyle, Helen Dolk. Published: December 1, 2016.  This article was cited in the textbook, The Maudsley Prescribing Guidelines in Psychiatry. Authors Taylor D., Barnes T., Young A. 2018. 13th Edition, Wiley Blackwell, Oxford p. 606


Identifying signals of potentially harmful medications in pregnancy: use of the double false discovery rate method to adjust for multiple testing. Cavadino A, Prieto-Merino D, Morris JKBr J Clin Pharmacol. 2018 Oct 23. doi: 10.1111/bcp.13799


First Trimester medication use in pregnancy in Cameroon: a multi-hospital surveyAminkeng Zawuo Leke, Helen Dolk, Maria Loane, Karen Casson, Nkwati Michel Maboh, Susan Etta Maeya, Lerry Dibo Ndumbe, Pauline Bessem Nyenti, Obale Armstrong and Derick Etiendem. BMC Pregnancy and Childbirth 2018. 18: 450



The EUROmediSAFE Inventory is now available.   This inventory is for evaluating the long-term risks for children associated with in-utero exposure.



Metformin exposure in first trimester of pregnancy and risk of all or specific congenital anomalies: exploratory case-control study.  Given JE, Loane M, Garne E, Addor MC, Bakker M, Bertaut-Nativel B, Gatt M, Klungsoyr K, Lelong N, Morgan M, Neville AJ, Pierini A, Rissmann A, Dolk H. BMJ 2018;361:k2477